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Effect of norepinephrine on RhoA, MAP kinase, proliferation and VEGF expression in human umbilical vein endothelial cells

✍ Scribed by Yumi Seya; Toshiyuki Fukuda; Kazumasa Isobe; Yasushi Kawakami; Kazuhiro Takekoshi


Book ID
113586507
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
703 KB
Volume
553
Category
Article
ISSN
0014-2999

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When FGF-1 or FGF-2 and VEGF were added together, the mitogenic effect of FGF-1 or FGF-2 and VEGF on HUVEC was additive. However, when HUVECs were preincubated for 2 days with 10 ng/ml FGF-1 in the absence of VEGF, the Scatchard plot of [125I]VEGF binding sites was shifted to the right: both affinit