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The Dynamics of the B−A Transition of Natural DNA Double Helices

✍ Scribed by Jose, Davis; Porschke, Dietmar


Book ID
127360807
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
261 KB
Volume
127
Category
Article
ISSN
0002-7863

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## Abstract Phosphorothioate oligonucleotides (PS–ODNs) have gained considerable attention in drug therapy, primarily as potent antisense or antigene oligomers, which bind to specific DNA or mRNA sequences and lead to transcriptional or translational arrest. These are obtained by substituting one o