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The dopamine D3 receptor as a novel target for antipsychotics

✍ Scribed by Schwartz, J.C; Sokoloff, P; Giros, B; Martres, M.P; Andrieux, M; Besançon, R; Bouthenet, M.L

Book ID
123292635
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
229 KB
Volume
1
Category
Article
ISSN
0924-977X

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✍ Sokoloff, Pierre; Giros, Bruno; Martres, Marie-Pascale; Bouthenet, Marie-Louise; 📂 Article 📅 1990 🏛 Nature Publishing Group 🌐 English ⚖ 887 KB

A dopamine receptor has been characterized which differs in its pharmacology and signalling system from the D1 or D2 receptor and represents both an autoreceptor and a postsynaptic receptor. The D3 receptor is localized to limbic areas of the brain, which are associated with cognitive, emotional and