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Dopamine D3 receptor as a new pharmacological target for the treatment of depression

✍ Scribed by Leggio, Gian Marco; Salomone, Salvatore; Bucolo, Claudio; Platania, Chiara; Micale, Vincenzo; Caraci, Filippo; Drago, Filippo


Book ID
120667266
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
483 KB
Volume
719
Category
Article
ISSN
0014-2999

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A dopamine receptor has been characterized which differs in its pharmacology and signalling system from the D1 or D2 receptor and represents both an autoreceptor and a postsynaptic receptor. The D3 receptor is localized to limbic areas of the brain, which are associated with cognitive, emotional and