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The dopamine D1 receptor agonist SKF 38393 suppresses detrusor hyperreflexia in the monkey with parkinsonism induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

✍ Scribed by N. Yoshimura; E. Mizuta; S. Kuno; M. Sasa; O. Yoshida


Book ID
116037563
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
476 KB
Volume
32
Category
Article
ISSN
0028-3908

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## Abstract At present, the pharmacotherapy of Parkinson's disease (PD) consists mainly of L‐dihydroxyphenylalanine (L‐DOPA) and/or dopamine D~2~ receptor agonist. However, in general the clinical efficacy of D~2~ agonists is less than that of L‐DOPA. Therefore, attention is being focussed on the r