Treatment of AS52 cells with 5azacytidine resulted in an induction of 6-thioguanine-resistant (6TG') colonies, which reached a maximum by an expression time of 9 days. Dose responses for both cytotoxicity and mutation induction were determined following treatment with Sazacytidine. At 20 pM treatmen
β¦ LIBER β¦
The DNA methylation inhibitor 5-azacytidine modulates 6-thioguanine toxicity in mammalian cells
β Scribed by Giulia Sciandrello; Fabio Caradonna; Giusi Barbata
- Book ID
- 119537543
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 221 KB
- Volume
- 142
- Category
- Article
- ISSN
- 0378-4274
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
5-Azacytidine-induced 6-thioguanine resi
β
Diane L. Spencer; William J. Caspary; Kimberly C. Hines; Kenneth R. Tindall
π
Article
π
1996
π
John Wiley and Sons
π
English
β 670 KB
Effect of an inhibitor of DNA methylatio
β
Richardson, Bruce
π
Article
π
1986
π
Elsevier Science
π
English
β 927 KB
Oxidation-Mediated DNA Cross-Linking Con
β
Brem, R.; Karran, P.
π
Article
π
2012
π
American Association for Cancer Research
π
English
β 828 KB
The mutagenicity of 5-azacytidine and ot
β
D.E. Amacher; G.N. Turner
π
Article
π
1987
π
Elsevier Science
π
English
β 562 KB
Site-specific mutagenesis of the N-(deox
β
S. Shibutani; Andrea Fernandes; Naomi Suzuki; L. Zhou; Francis Johnson; Arthur P
π
Article
π
1998
π
Springer
π
English
β 95 KB
2-hydroxyamino-1-methyl-6-phenylimidazo
β
Tomoji Kitazawa; Ryo Kominami; Ryuichi Tanaka; Keiji Wakabayashi; Minako Nagao
π
Article
π
1994
π
John Wiley and Sons
π
English
β 360 KB
## Abstract 2βAminoβ1βmethylβ6βphenylimidazo[4,5β__b__]pyridine (PhIP) is the most abundant mutagenic heterocyclic amine in cooked foods. Two mouse tumor cell lines, BMT11 and FM3A, were exposed to its proximate form, 2βhydroxyaminoβ1βmethylβ6βphenylimidazo[4,5β__b__]pyridine (__N__βOHβPhIP). Fifty