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The DNA damage-dependent intra–S phase checkpoint is regulated by parallel pathways

✍ Scribed by Falck, Jacob; Petrini, John H.J.; Williams, Bret R.; Lukas, Jiri; Bartek, Jiri

Book ID
118676035
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
476 KB
Volume
30
Category
Article
ISSN
1061-4036

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## Abstract We have studied the rate of DNA synthesis, cell cycle distribution, formation of γ‐H2AX, and Rad51 nuclear foci and association of Rad51 with the nuclear matrix after treatment of HeLa cells with the interstrand crosslinking agent mitomycin C (MMC) in the presence of the kinase inhibito