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PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2

โœ Scribed by Yang, Shutong; Kuo, Christin; Bisi, John E.; Kim, Myung K.


Book ID
109912636
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
697 KB
Volume
4
Category
Article
ISSN
1465-7392

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โœ Jong-Hee Lee; Kyong-Tai Kim ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 572 KB

## Abstract DNA damage is known to be an initiator of neuronal death in neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. The mechanism linking DNA damage and neuronal death is not completely understood. Here, we delineate the mechanism by which neuronal death evoked by DNA