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Phosphorylation of BRCA2 by the Polo-like kinase Plk1 is regulated by DNA damage and mitotic progression

โœ Scribed by Lee, MiYoung; Daniels, Matthew J; Venkitaraman, Ashok R


Book ID
110068304
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
293 KB
Volume
23
Category
Article
ISSN
0950-9232

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โœ Jong-Hee Lee; Kyong-Tai Kim ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 572 KB

## Abstract DNA damage is known to be an initiator of neuronal death in neurodegenerative conditions such as Parkinson's and Alzheimer's diseases. The mechanism linking DNA damage and neuronal death is not completely understood. Here, we delineate the mechanism by which neuronal death evoked by DNA