β Scribed by Sperandio, G.J. ;Evanson, R.V. ;Dekay, H.G.
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π SIMILAR VOLUMES
The inΒ―uence of compression force to inner core tablet or to outer coating layer of the compression-coated tablet on the function of time-controlled disintegration was investigated. The inner core tablet was directly compacted by sodium diclofenac (model drug) and ethylcellulose (EC) with 4.6-mm par
The effect of excipient, drug, and osmotic agent loaded in the inner core tablet on the time-controlled disintegration of compression-coated tablet prepared by direct compression with micronized ethylcellulose was investigated. The excipients [spray-dried lactose, hydroxypropyl methyl cellulose, sod
T h e effect of compressin several mesh sizes of lactose, sodium bicarEonate, and magnesium trisilicate granulations into tablets was determined. A definite relationship was found to exist between the particle size of the granulation of a particular substance and the disintegration rate, per cent of