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The discovery of a mevalonate-independent pathway for isoprenoid biosynthesis in bacteria, algae and higher plants†

✍ Scribed by Rohmer, Michel; Rohmer, Michel


Book ID
115475159
Publisher
Royal Society of Chemistry
Year
1999
Tongue
English
Weight
153 KB
Volume
16
Category
Article
ISSN
0265-0568

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Chemical Synthesis of Enantiopure 2-C-Me
✍ Jean-François Hoeffler; C Pale-Grosdemange; Michel Rohmer 📂 Article 📅 2000 🏛 Elsevier Science 🌐 French ⚖ 117 KB

Optically pure 2-C-methyl-d-erythritol 4-phosphate, a key intermediate in the mevalonate-independent route for isoprenoid biosynthesis, is conveniently synthesized from 1,2-O-isopropylidene-a-d-xylofuranose, including the possibility of radiolabeling of this substrate.