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The directed metalation connection to aryl-aryl cross coupling.Regiospecific synthesis of phenanthridines, phenanthridinones and the biphenyl alkaloid ismine

✍ Scribed by M.A. Siddiqui; V. Snieckus


Publisher
Elsevier Science
Year
1988
Tongue
French
Weight
230 KB
Volume
29
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES


Synthetic connections to the aromatic di
✍ M.J. Sharp; V. Snieckus πŸ“‚ Article πŸ“… 1985 πŸ› Elsevier Science 🌐 French βš– 219 KB

The arylboronic acids 2 and 4 derived by directed ortho metalation of benzamides and carbamates, undergo an efficient palladium-catalyzed cross coupling reaction with a variety of aryl halides to yield unsymmetrical biaryls and heterobiaryls (Table ).

Synthetic connections to the aromatic di
✍ M.J. Sharp; W. Cheng; V. Snieckus πŸ“‚ Article πŸ“… 1987 πŸ› Elsevier Science 🌐 French βš– 272 KB

Aryl boronic acids 2a-d and la-d obtained by metalation-B(OMe)s or metalation silylation-ipso borodesilylation sequences, participate in efficient Pd'-catalyzed cross coupling reactions with aryl bromides to give unsymmetrical biphenyls 3a-d and m\_terphenyls 5a-d respectively. We have recently des