The directed metalation connection to aryl-aryl cross coupling.Regiospecific synthesis of phenanthridines, phenanthridinones and the biphenyl alkaloid ismine
β Scribed by M.A. Siddiqui; V. Snieckus
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- French
- Weight
- 230 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0040-4039
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π SIMILAR VOLUMES
The arylboronic acids 2 and 4 derived by directed ortho metalation of benzamides and carbamates, undergo an efficient palladium-catalyzed cross coupling reaction with a variety of aryl halides to yield unsymmetrical biaryls and heterobiaryls (Table ).
Aryl boronic acids 2a-d and la-d obtained by metalation-B(OMe)s or metalation silylation-ipso borodesilylation sequences, participate in efficient Pd'-catalyzed cross coupling reactions with aryl bromides to give unsymmetrical biphenyls 3a-d and m\_terphenyls 5a-d respectively. We have recently des
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