✦ LIBER ✦

Synthetic connections to the aromatic directed metalationreaction. Unsymmetrical biaryls by palladium-catalyzed cross coupling of directed metalation-derived arylboronic acids with aryl halides

✍ Scribed by M.J. Sharp; V. Snieckus

Publisher: Elsevier Science
Year: 1985
Tongue: French
Weight: 219 KB
Volume: 26
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)95108-6

No coin nor oath required. For personal study only.

✦ Synopsis

The arylboronic acids 2 and 4 derived by directed ortho metalation of benzamides and carbamates, undergo an efficient palladium-catalyzed cross coupling reaction with a variety of aryl halides to yield unsymmetrical biaryls and heterobiaryls (Table ).

📜 SIMILAR VOLUMES

Synthetic connections to the aromatic di

Synthetic connections to the aromatic directed metalation reaction. Functionalized aryl boronic acids by ipso borodesilylation. General syntheses of unsymmetrical biphenyls and m-terphenyls

✍ M.J. Sharp; W. Cheng; V. Snieckus 📂 Article 📅 1987 🏛 Elsevier Science 🌐 French ⚖ 272 KB

Aryl boronic acids 2a-d and la-d obtained by metalation-B(OMe)s or metalation silylation-ipso borodesilylation sequences, participate in efficient Pd'-catalyzed cross coupling reactions with aryl bromides to give unsymmetrical biphenyls 3a-d and m\_terphenyls 5a-d respectively. We have recently des