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The development of non-peptide glucagon-like peptide-1 receptor agonist for the treatment of type 2 diabetes

✍ Scribed by Ho-Sang Moon; Mi-Kyung Kim; Moon-Ho Son


Book ID
107642517
Publisher
Springer
Year
2011
Tongue
English
Weight
620 KB
Volume
34
Category
Article
ISSN
0253-6269

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Glucagon-like peptide-1 (GLP-1) is a hormone derived from the preproglucagon molecule that is secreted by intestinal L cells and stimulates insulin secretion from beta cells. The GLP-1 receptor is a candidate gene for diabetes mellitus, as mutations may induce the impaired insulin response that is a