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Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

✍ Scribed by M. A. Nauck; I. Vardarli; C. F. Deacon; J. J. Holst; J. J. Meier

Book ID
105819990
Publisher
Springer
Year
2010
Tongue
English
Weight
294 KB
Volume
54
Category
Article
ISSN
0012-186X

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GLP-1, an incretin hormone of the enteroinsular axis with insulinotropic and glucagonostatic activity, is secreted after nutrient ingestion. GLP-1 is mainly produced by intestinal L-cells in the lower gastrointestinal tract (GIT); simple carbohydrates are absorbed in the upper GIT and ␣-glucosidase