The development of a C-terminal sequencer
β Scribed by Hans-Arthur Bradaczek; Brigitte Wittmann-Liebold
- Publisher
- Springer
- Year
- 1992
- Tongue
- English
- Weight
- 122 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1573-4943
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π SIMILAR VOLUMES
We describe the construction of a compact protein sequencer designed specifically for the C-terminal sequence analysis of peptides and proteins. This sequencer has a vertical flow path and is equipped with a continuous flow reactor (CFR). The flow paths for the various reagents and solvents have bee
## Abstract A synthesis is described of the partially protected carboxylβterminal tetrapeptide sequence, LβleucylβLβmethionylβLβasparaginylβOβtβbutylβLβthreonine tβbutyl ester, which is derived from the pancreatic hormone glucagon. In this synthesis we used successfully a novel combination of bloc