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The determination of the velocity of hydrolysis of acid anhydrides by the aniline-water method. I

โœ Scribed by S. E. Vles


Book ID
104585493
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
772 KB
Volume
52
Category
Article
ISSN
0165-0513

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Hydrolysis in the absence of bulk water
โœ Jefferson T. Eaton; William D. Rounds; John H. Urbanowicz; Gordon W. Gribble ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 252 KB

The reaction of primary and secondary amides with tetrafluorophthalic or tetrachlorophthalic anhydride gives carboxylic acids in good yield. The reaction is chemoselective in that the amide functionality can be hydrolyzed in the presence of ester groups. We report that the prototypical reaction bet