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The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine.

✍ Scribed by L Bertilsson; A Aberg-Wistedt

Book ID
117943099
Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
442 KB
Volume
15
Category
Article
ISSN
0306-5251

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A sensitive and specific method for the simultaneous determination of imipraminc and desipramine in the blood plasma of depressed patients under treatment that involves separation by gas chromatography and detection by mass fragmentography is described. Concentrations were determined by focusing the