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The death of a T-cell: expression of the CD95 ligand

✍ Scribed by Li-Weber, M; Krammer, P H

Book ID
110016333
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
91 KB
Volume
9
Category
Article
ISSN
1350-9047

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Tumors of diverse origin have recently been shown to express CD95 ligand and to induce apoptosis in CD95-expressing targets in vitro; however, in vivo, enhanced tumor growth and rejection have both been observed as a consequence of either immunosuppressive or proinflammatory functions of CD95 ligand