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The D2 agonist quinpirole potentiates the discriminative stimulus effects of the D1 agonist SKF 38393

✍ Scribed by Joseph E.G. Williams; William L. Woolverton

Book ID
113223941
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
516 KB
Volume
37
Category
Article
ISSN
0091-3057

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The D1dopamine agonist SKF 38393 functio
The D1dopamine agonist SKF 38393 functions as a discriminative stimulus in rats
✍ Jonathan B. Kamien; William L. Woolverton πŸ“‚ Article πŸ“… 1985 πŸ› Springer 🌐 English βš– 264 KB

Rats (N = 11) were trained to discriminate SKF 38393 (8.0 mg/kg, IP), a D1 dopamine receptor agonist, from saline in a two-lever, food-reinforced (FR 30) drug discrimination paradigm. The discrimination was acquired by nine rats within an average of 77 +/- 6 (SEM) sessions. Subsequently, various dos