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Evidence for postsynaptic dopamine agonist effects of B-HT 920 in the presence of the dopamine D-1 agonist SKF 38393

โœ Scribed by Leonard T. Meltzer; James N. Wiley; Ann E. Williams; Thomas G. Heffner


Publisher
Springer
Year
1988
Tongue
English
Weight
403 KB
Volume
95
Category
Article
ISSN
0033-3158

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The effects of the D-1 agonist SKF 38393 on tonic activity of rat substantia nigra pars compacta dopamine neurons were studied using extracellular, single-unit recording techniques. Unlike nonselective D-1/D-2 dopamine agonists or the D-2 agonist quinpirole, SKF 38393 did not inhibit dopamine neuron