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Inhibition of dopamine synthesis in striatal slices by the D1 agonist SKF 38393 is not mediated by D1 dopamine receptors

โœ Scribed by Richard J. Brooderson; Francis J. White; Dr. Mathew P. Galloway


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
335 KB
Volume
6
Category
Article
ISSN
0887-4476

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โœ Michael P. Hill; Paula Ravenscroft; Steven G. McGuire; Jonathan M. Brotchie; Ala ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 95 KB

L-dopa remains the most common treatment for Parkinson's disease. However, there is considerable interest in D3/D2 receptor agonists such as the novel agent S32504, since they exert antiparkinsonian properties in the absence of dyskinesia. An important question concerns the roles of D2 vs. D3 recept