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Dopamine D1 receptor mediation of the discriminative stimulus properties of SKF 38393

โœ Scribed by Kathryn A. Cunningham; Patrick M. Callahan; James B. Appel

Book ID
115879238
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
323 KB
Volume
119
Category
Article
ISSN
0014-2999

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The D1dopamine agonist SKF 38393 functio
The D1dopamine agonist SKF 38393 functions as a discriminative stimulus in rats
โœ Jonathan B. Kamien; William L. Woolverton ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› Springer ๐ŸŒ English โš– 264 KB

Rats (N = 11) were trained to discriminate SKF 38393 (8.0 mg/kg, IP), a D1 dopamine receptor agonist, from saline in a two-lever, food-reinforced (FR 30) drug discrimination paradigm. The discrimination was acquired by nine rats within an average of 77 +/- 6 (SEM) sessions. Subsequently, various dos