๐”– Bobbio Scriptorium
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The conversion of 2-dimethylamino-1,3-dioxolans into alkenes

โœ Scribed by F.W. Eastwood; K.J. Harrington; J.S. Josan; J.L. Pura


Book ID
104230070
Publisher
Elsevier Science
Year
1970
Tongue
French
Weight
98 KB
Volume
11
Category
Article
ISSN
0040-4039

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Cyclofunctionalisation of epoxyalcohol d
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2,3-Epoxyalcohols react with paraformaldehyde and either cesium carbonate or potassium carbonate/phase-transfer catalyst in polar, aprotic solvents to give excellent yields of 4-(1-hydroxyalkyl)-1,3-dioxolanes, with inversion at C-2. Carbonates and carbamates of 2,3-epoxyalcohols undergo cyclisation