We describe a method for incorporating pharmacokinetic (PK) data into dose escalation clinical trial designs. Doing so can improve the efficiency and accuracy of these studies. The method proposed uses a parametric dose response function that models the probability of response in each person with tw
โฆ LIBER โฆ
The construction of optimal designs for dose-escalation studies
โ Scribed by Linda M. Haines, Allan E. Clark
- Book ID
- 120779341
- Publisher
- Springer US
- Year
- 2012
- Tongue
- English
- Weight
- 381 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0960-3174
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