Received in USA 1st Mgust ~63; -rec&ved in UK for publication 6th titober 1969) There has been considerable recent interest in the solution conformation of macrolide antibiotics based upon the reasonable expectation that this knowledge would lead to deeper insight into their chemical, physical and b
The conformation of macrolide antibiotics II. Configurational and conformational studies of dihydroerythronolides
โ Scribed by Thomas J. Perun; Richard S. Egan; Jerry R. Martin
- Publisher
- Elsevier Science
- Year
- 1969
- Tongue
- French
- Weight
- 229 KB
- Volume
- 10
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
โฆ Synopsis
Nuclear magnetic resonance techniques have recently been applied to the determination of the solution conformation of the 14-membered lactone in the erythromycin series (1,2), and the conformations revealed by these independent studies are in substantial agreement. One
๐ SIMILAR VOLUMES
As a result of the x-ray single crystal analysis of N-iodoacetylamphotericin B the chemical and stereochemical absolute structure ia presented (I). A similar etructure and stereochemistry wae extended to the parent compound itself, amphotericin B, a heptaene macrolide antifungal antibiotic possessin
Tetrahedron Letters No. 41. pp. 3601-3604 (1970) p. 3529 W. Sprenger was omitted from the "Contributors to this issue" W. MECHLINSKI, C. P. SCHAFFNER, P. GANIS and G. AVITABILE: Structure and absolute configuration of the polyene macrolide antibiotic amphotericin B.