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The competitive inhibition of tissue transglutaminase by α-difluoromethylornithine

✍ Scribed by Jean-Guy Delcros; Anne-Marie Roch; Gérard Quash


Book ID
115915666
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
594 KB
Volume
171
Category
Article
ISSN
0014-5793

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A large body of evidence exists suggesting that polyamines can play essential roles in cellular growth and differentiation. We examined the ability of alpha-difluoromethylornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, the major rate-limiting enzyme in polyamine biosynthesis,