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The clinical role of phospholipase A2 isoforms in advanced-stage ovarian carcinoma

✍ Scribed by Michal Gorovetz; Mark Baekelandt; Aasmund Berner; Claes G. Trope'; Ben Davidson; Reuven Reich

Book ID
113960728
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
691 KB
Volume
103
Category
Article
ISSN
0090-8258

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## Abstract ## BACKGROUND Cyclooxygenase‐2 (COX‐2) seems to be involved at various steps in the processes of malignant transformation and tumor progression. Investigations have shown that COX‐2 overexpression is associated with increased proliferation, reduced apoptosis, and angiogenesis. ## METH