𝔖 Bobbio Scriptorium
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The role of hexamethylmelamine in advanced ovarian carcinoma treatment

✍ Scribed by Raymond B. Weiss


Book ID
119052071
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
608 KB
Volume
12
Category
Article
ISSN
0090-8258

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Hexamethylmelamine and melphalan as salv
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## Abstract Ten patients with advanced ovarian carcinoma were treated with hexa‐methylmelamine and melphalan after failing first‐line combination chemotherapy. In eight patients residual disease was evident only at second‐look laparotomy. Surgical debulking was accomplished in four patients but onl

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Fifty-three evaluable patients with disseminated ovarian carcinoma (FIGO Ill or IV) not treated with prior chemotherapy were randomized to receive either combination chemotherapy consisting of cis-platinum 40 mg/m e IV on day 1, adriamycin 40 mg/m 2 IV on day 1, and hexamethylmelamine 150 mg/m 2 PO