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The AP-2γ transcription factor is upregulated in advanced-stage ovarian carcinoma

✍ Scribed by Elin Ødegaard; Anne Cathrine Staff; Janne Kærn; Vivi Ann Flørenes; Juri Kopolovic; Claes G. Tropé; Vera M. Abeler; Reuven Reich; Ben Davidson


Book ID
113960274
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
346 KB
Volume
100
Category
Article
ISSN
0090-8258

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## Abstract ## BACKGROUND Cyclooxygenase‐2 (COX‐2) seems to be involved at various steps in the processes of malignant transformation and tumor progression. Investigations have shown that COX‐2 overexpression is associated with increased proliferation, reduced apoptosis, and angiogenesis. ## METH