The Chiral Synthesis of Thiazole Amino Acid Enantiomers
โ Scribed by Bredenkamp, Martin W.; Holzapfel, Cedric W.; van Zyl, Wynand J.
- Book ID
- 118247098
- Publisher
- Taylor and Francis Group
- Year
- 1990
- Tongue
- English
- Weight
- 542 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0039-7911
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๐ SIMILAR VOLUMES
IN connexion with our studies on the antibiotic, Thiostrepton,' we have prepared a number of 2-(a-aminoalkyl)-thiazole-4-carboxylic acids (I, R=H, Me, Et end CHMe2). Since thiazole structures have been advanced for degradation products of other peptide antibiotics, 2,j a brief account of our results
Chelate-like association of amino acid derivatives made up by intermolecular NH\*\*O=C hydrogen bonds can function as chiroselective complexation for resolution of D-and L-amino acid derivatives. Recognition of molecular chiralities is made on the basis of the different affinities of chiral molecule