𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The Chemical Reactivity of β-Lactams, β-Sultams and β-Phospholactams

✍ Scribed by Michael I. Page; Andrew P. Laws

Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
137 KB
Volume
56
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

AbstractÐb-Lactam antibiotics display a range of biological activities. The origin of this diverse biological activity is discussed with reference to the chemical reactivity of the small ring system. The reactions of b-sultams and b-phospholactams with simple nucleophiles are reported and their potential as mechanism based inhibitors of bacterial and mammalian serine proteases is described.

📜 SIMILAR VOLUMES

Synthesis of Bicyclic β-Sultams
Synthesis of Bicyclic β-Sultams
✍ Dr. Friedrich Cavagna; Dr. Wolfgang Koller; Dr. Adolf Linkies; Dr. Herbert Rehli 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB 👁 1 views
Synthesis of Bicyclic β-Sultams
Synthesis of Bicyclic β-Sultams
✍ Dr. Friedrich Cavagna; Dr. Wolfgang Koller; Dr. Adolf Linkies; Dr. Herbert Rehli 📂 Article 📅 1982 🏛 John Wiley and Sons 🌐 English ⚖ 211 KB

## Of his 60th birthday It is generally assumed that the biological activity Of E-lactam antibiotics depends on the reactivity of the 6-lactam ring. substitution of the CO-group of the 8-lactam by the S02-group leads to 6-sultams which are more reactive than corresponding 6-lactams / l / . We wish

Synthesis and Properties of β-sultams
Synthesis and Properties of β-sultams
✍ Wolfgang Koller; Adolf Linkies; Herbert Rehling; Dieter Reuschling 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 188 KB

B-Sultams substituted in 2and 3-position including bicyclic B-sultams were prepared and some of their reactions are reported.

Hydrates and Solid-State Reactivity: β-L
Hydrates and Solid-State Reactivity: β-Lactam Antibiotics
✍ Magali B. Hickey; Matthew L. Peterson; Eric S. Manas; Juan Alvarez; Fredrik Haef 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 11 KB

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.