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The cellular response to p53: the decision between life and death

โœ Scribed by Sionov, Ronit Vogt; Haupt, Ygal


Book ID
110062498
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
226 KB
Volume
18
Category
Article
ISSN
0950-9232

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Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu