𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Hypoxia attenuates the p53 response to cellular damage

✍ Scribed by Achison, Marcus; Hupp, Ted R


Book ID
110067541
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
352 KB
Volume
22
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


BTG gene expression in the p53-dependent
✍ Ulrich Cortes; Caroline Moyret-Lalle; Nicole Falette; Cyril Duriez; Fatiha El Gh πŸ“‚ Article πŸ“… 2000 πŸ› John Wiley and Sons 🌐 English βš– 250 KB

Exposure of mammalian cells to genotoxic agents evokes a complex cellular response. An ordered series of molecular events is necessary to sense DNA damage, transduce the signal, and ultimately delay the cell cycle or trigger apoptosis. Recently, we have shown that BTG2/TIS21 gene expression was indu

Regulation of p53 in response to DNA dam
✍ Lakin, Nicholas D; Jackson, Stephen P πŸ“‚ Article πŸ“… 1999 πŸ› Nature Publishing Group 🌐 English βš– 340 KB
p53 modulation of the DNA damage respons
✍ E. Scott Helton; Xinbin Chen πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 338 KB

## Abstract The tumor suppressor p53 plays a central role in the DNA damage response. After exposure to genotoxic stress, p53 can both positively and negatively regulate cell fate. Initially, p53 promotes cell survival by inducing cell cycle arrest, DNA repair, and other pro‐survival pathways. Howe