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The CD3γ chain is essential for development of both the TCRαβ and TCRγδ lineages

✍ Scribed by Haks, Mariëlle C.; Krimpenfort, Paul; Borst, Jannie; Kruisbeek, Ada M.

Book ID
119770341
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
915 KB
Volume
17
Category
Article
ISSN
0261-4189

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Several groups have described that a low percentage of in vitro cultured Tcell receptor (TcR) yl6 cells express CD8. Contrary toTcR alp cells, however, CD8 on these TcR y/6 cells was shown to be a CD8a homodimer. We describe here that addition of interleukin-7 (IL-7) to a short-term in vitro culture