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Thymocytes Expressing Both αβ and γδ TCRs: Implications for Models of Lineage Commitment

✍ Scribed by Chong-kil Lee; Kyungjae Kim; Kathrin Muegge; Scott K. Durum


Book ID
117410632
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
714 KB
Volume
17
Category
Article
ISSN
0197-1859

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Assembly of the TCR/CD3 complex: CD3ϵ/δ
✍ Ester San José; Almudena G. Sahuquillo; Rafael Bragado; Balbino Alarcón 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 188 KB

The TCR/CD3 complex is composed of six subunits which are expressed on the cell surface in a coordinate fashion after assembly in the endoplasmic reticulum (ER). The TCR/CD3 complex is assembled after a series of pairwise interactions involving the formation of dimers of CD3 epsilon with either CD3