A new model for catalysis of human carbonic anhydrase II is suggested. The model is based on the X-ray structure of the hydrogen bond network in the catalytic site. The outer part of the network is proposed to adjust the pK a of the catalytic site to the experimentally observed value of about 7. The
✦ LIBER ✦
The Catalytic Mechanism of Carbonic Anhydrase : Hydrogen-Isotope Effects on the Kinetic Parameters of the Human C Isoenzyme
✍ Scribed by Håkan STEINER; Bengt-Harald JONSSON; Sven LINDSKOG
- Book ID
- 115114754
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 620 KB
- Volume
- 59
- Category
- Article
- ISSN
- 1432-1327
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