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The C-terminal region of Escherichia coli MutS and protein oligomerization

✍ Scribed by Virginia Miguel; Roberto J. Pezza; Carlos E. Argaraña

Book ID
116295207
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
358 KB
Volume
360
Category
Article
ISSN
0006-291X

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High levels of expression of oligomeric proteins in heterologous systems are frequently associated with misfolding and accumulation of the polypeptides in inclusion bodies. This reflects aspects of the folding and assembly pathways of oligomeric proteins, which generally proceed from either folding