The biosynthesis of the antibiotic obafl
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Richard B. Herbert; Andrew R. Knaggs
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Article
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1988
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Elsevier Science
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French
β 209 KB
The separate units which are used to construct the unique p-lactone antibiotic obafluorin (1) in Pseudomonas jluorescens are defined by the results of [v-13C]glucose incorporation. A key intermediate in the biosynthesis of ( 1) is established to be L-p-aminophenylalanine (7); L-p-nitrophenylalanine