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The biosynthesis of the pseudomonas antibiotic obafluorin from p-aminophenylalanine and glycine (glyoxylate)

✍ Scribed by Richard B. Herbert; Andrew R. Knaggs


Book ID
104221851
Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
285 KB
Volume
31
Category
Article
ISSN
0040-4039

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The biosynthesis of the antibiotic obafl
✍ Richard B. Herbert; Andrew R. Knaggs πŸ“‚ Article πŸ“… 1988 πŸ› Elsevier Science 🌐 French βš– 209 KB

The separate units which are used to construct the unique p-lactone antibiotic obafluorin (1) in Pseudomonas jluorescens are defined by the results of [v-13C]glucose incorporation. A key intermediate in the biosynthesis of ( 1) is established to be L-p-aminophenylalanine (7); L-p-nitrophenylalanine