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Biosynthesis of the antibiotic obafluorin from D-[U-13C]glucose and p-aminophenylalanine in Pseudomonas fluorescens

โœ Scribed by Herbert, Richard B.; Knaggs, Andrew R.


Book ID
121230573
Publisher
Royal Society of Chemistry
Year
1992
Weight
712 KB
Volume
1
Category
Article
ISSN
1472-7781

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The biosynthesis of the antibiotic obafl
โœ Richard B. Herbert; Andrew R. Knaggs ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 209 KB

The separate units which are used to construct the unique p-lactone antibiotic obafluorin (1) in Pseudomonas jluorescens are defined by the results of [v-13C]glucose incorporation. A key intermediate in the biosynthesis of ( 1) is established to be L-p-aminophenylalanine (7); L-p-nitrophenylalanine