The biology of interleukin 1 and comparison to tumor necrosis factor
β Scribed by Charles A. Dinarello
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- English
- Weight
- 419 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0165-2478
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
With concomitant methotrexate. β Pegylated recombinant methionyl human soluble tumor necrosis factor type I.
The proinflammatory cytokines interleukin-1 and tumor necrosis factor-alpha are thought to play important roles in the pathophysiology of liver disease. Specific antagonists of these cytokines have been found in recent years. Interleukin-1 receptor antagonist is a specific interleukin-1 antagonist.
Monocyte/macrophage polypeptides (monokines) alter the properties of synovial cells. This interaction could explain some of the properties of the inflamed synovium in rheumatic disease. Only recently has it been possible to test the action of purified monokines on the target synovial cells. We repor