CD4, CD8 and CD45 regulate the coupling of the T-cell receptor complex (CD3-TCR) to tyrosine kinase activation and phosphorylation of key substrates such as phospholipase C gamma 1. CD4 and CD8 contribute to activation signals through their cytoplasmic association with p56lck. Expression of the zeta
โฆ LIBER โฆ
The Biologic Roles of CD2, CD4, and CD8 in T-Cell Activation
โ Scribed by Bierer, B E; Sleckman, B P; Ratnofsky, S E; Burakoff, S J
- Book ID
- 124051585
- Publisher
- Annual Reviews
- Year
- 1989
- Tongue
- English
- Weight
- 593 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0732-0582
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