The Big Blue® transgenic mouse mutation detection assay: the mutation pattern of sectored mutant plaques
✍ Scribed by Kathleen A Hill; Hiroshi Nishino; Victoria L Buettner; Asanga Halangoda; Wenyan Li; Steve S Sommer
- Book ID
- 114072460
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 98 KB
- Volume
- 425
- Category
- Article
- ISSN
- 0027-5107
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Three genotoxic mouse carcinogens, 4 c h l o r wphenylenediamine (4-C-o-PDA), 2-nitro-p-phenylenediamine (2-N-pPDA), and 2,4diaminotoluene (2,4-DAT), were tested in the Big BlueTM transgenic mouse mutation assay. Each experiment consisted of a vehicle control group with ten Big BlueTM C57BL/6 mice,