Evaluation of the in vivo genotoxic potential of 3 carcinogenic aromatic amines using the Big Blue transgenic mouse mutation assay

System issues: Evaluation of the in vivo

System issues: Evaluation of the in vivo genotoxic potential of three carcinogenic aromatic amines using the Big Blue™ transgenic mouse mutation assay

✍ W. Suter; R. Ahiabor; B. Blanco; F. Locher; F. Mantovani; M. Robinson; G. Sreena 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 692 KB

Three genotoxic mouse carcinogens, 4 c h l o r wphenylenediamine (4-C-o-PDA), 2-nitro-p-phenylenediamine (2-N-pPDA), and 2,4diaminotoluene (2,4-DAT), were tested in the Big BlueTM transgenic mouse mutation assay. Each experiment consisted of a vehicle control group with ten Big BlueTM C57BL/6 mice,