๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice

โœ Scribed by Y Paashuis-Lew; X.B Zhang; J.A Heddle


Book ID
114071139
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
228 KB
Volume
373
Category
Article
ISSN
0027-5107

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


System issues: The genetic analysis of l
โœ Gregory R. Stuart; Nancy J. Gorelick; Julie L. Andrews; Johan G. de Boer; Barry ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 761 KB

However, the interpretation of data from transgenic animal assays is sometimes complicated by mutants that appear as sectored mutant lambda plaques. These mutants can form a significant fraction of the mutant plaques [Hayward et al. (1 995): Carcinogenesis 16:2429-24331. Thus, in order to accurately

Spontaneous mutation spectrum at the lam
โœ P.R. Harbach; D.M. Zimmer; A.L. Filipunas; W.B. Mattes; C.S. Aaron ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 241 KB ๐Ÿ‘ 2 views

Big Blue ยฎ mice harbor a recoverable transgene in a lambda/LIZ shuttle vector. In the standard assay, in vivo mutations are measured in the bacterial lacI gene using a labor-intensive color plaque assay. Applying a simpler assay : Proc Natl Acad Sci USA 93:9073-9078], we measured mutations in the la