The relative contribution to development of hepatocellular carcinoma of the mouse equivalent to the human p53ser249 mutation, found in human hepatocellular carcinoma associated with aflatoxin (AFB1) exposure, is compared with other major risk factors in a transgenic mouse model. Transgenic p53ser246
Spontaneous mutation frequencies and spectra in p53 (+/+) and p53 (−/−) mice: A test of the `guardian of the genome' hypothesis in the Big Blue® transgenic mouse mutation detection system
✍ Scribed by Victoria L Buettner; Hiroshi Nishino; Jan Haavik; Antje Knöll; Kathleen Hill; Steve S Sommer
- Book ID
- 114071280
- Publisher
- Elsevier Science
- Year
- 1997
- Tongue
- English
- Weight
- 70 KB
- Volume
- 379
- Category
- Article
- ISSN
- 0027-5107
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