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The base-catalyzed deuteration of n-methyl-4-pyridone

✍ Scribed by Peter Beak; James Bonham


Book ID
104240712
Publisher
Elsevier Science
Year
1964
Tongue
French
Weight
156 KB
Volume
5
Category
Article
ISSN
0040-4039

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Base-catalyzed deuterium and tritium lab
✍ Carl Berthelette; John Scheigetz πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 French βš– 78 KB

## Abstract A synthesis and a base‐catalyzed exchange reaction was developed under mild conditions to deuterate and subsequently tritiate the methyl group of the base sensitive diketone 1‐biphenyl‐4‐ylpropane‐l,2‐dione depicted in Figure 1. Using Et~3~N as base, deuterium incorporation of the methy