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The application of 2-(4-chlorophenyl)-sulfonylethoxycarbonyl (CPSEC) group in the synthesis of a DNA segment using the phosphotriester approach

✍ Scribed by Staffan Josephson; Neil Balgobin; Jyoti Chattopadhyaya

Publisher: Elsevier Science
Year: 1981
Tongue: French
Weight: 320 KB
Volume: 22
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(01)93035-7

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✦ Synopsis

The new base labile CPSEC group has been successfully employed for the protection of the 5'-hydroxyl function to synthesize a "universal Stop codon" DNA sequence: 5'd(TCAATCAATCA)3'.

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