## Abstract The androgen receptor signaling axis plays an essential role in the development, function and homeostasis of male urogenital structures including the prostate gland although the mechanism by which the AR axis contributes to the initiation, progression and metastatic spread of prostate c
β¦ LIBER β¦
The androgen receptor: genetic considerations in the development and treatment of prostate cancer
β Scribed by Kelly J. Cude; Shannon C. Dixon; Y. Guo; Jordan Lisella; W. D. Figg
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 105 KB
- Volume
- 77
- Category
- Article
- ISSN
- 0946-2716
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## BACKGROUND. The purpose of this study was to determine the contribution of different transactivating regions of the androgen receptor (AR) to the induction of androgen-regulated promoters in poorly (PC3 cells) and well-differentiated (LNCaP cells) prostate cancer cell lines. METHODS. PC3 and LN