The amplifier role of T cells in the human in vitro B cell response to type 4 pneumococcal polysaccharide
β Scribed by Arjan W. Griffioen; Elly A.H. Toebes; Ger T. Rijkers; Frans H.J. Claas; Gert Datema; Ben J.M. Zegers
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 594 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0165-2478
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract A reproducible __in vitro__ assay for the effect of suppressor T cells on the generation of an __in vitro__ cytotoxic response to a metastatic murine tumor is described. Suppression in this system is maximal. The model uses splenic T cells from DBA/2 mice bearing the MDAYβD2 metastatic
While most of the focus in cancer immunology is on CD8+ cytotoxic T lymphocyte responses, recent evidence indicates that CD4+ T cells are an equally critical component of the antitumor immune response. Successful immunity to cancer will therefore require activation of tumor-specific CD4+ T cells. Tu